ea0081p46 | Calcium and Bone | ECE2022
Gooijer Koert
, Heidsieck Gabriela
, Harsevoort Arjan
, Bout Danielle
, Janus Guus
, Franken Anton
Background: Osteogenesis Imperfecta (OI) is commonly defined as brittle bones disease, but there are also more characteristics like blue sclerae, hearing loss, dental problems, ligamentous laxity and a short stature. Easy bruising is also a very common feature and there are multiple case reports on haemorrhagic events in OI. Larger population studies on bleeding tendency in OI are very sparse, while other connective tissue disorders with easy bruising have much mor...